Talk:Two-component regulatory system

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Molecular Biology: MCB / Cell Signaling

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Change name of article to "Two-component regulatory system"[edit]

The mode of signal transduction described in this article is known as "two-component regulatory system(s)," not "two-component regulation system(s)." The title needs to be corrected. NighthawkJ (talk) 19:56, 21 April 2008 (UTC)[reply]

Since there are no objections, I went ahead and made the change. NighthawkJ (talk) 16:45, 3 September 2008 (UTC)[reply]

I think this is stated in the literature as "Two-component signal transduction system" (see titles of references). --kupirijo (talk) 19:40, 3 September 2018 (UTC)[reply]

Sensorcomponent[edit]

Is the sensor in two-component regulation really always a histidin kinase? Where is that information found? Akita86 (talk) 14:11, 28 January 2009 (UTC)[reply]

I haven't heard of any other type of kinase that mediates this function. Most of the references in the article have implicated Histidine kinase as the sensor in these systems. If you come across any other type of kinase please let me know so I can include it in the article for completeness.Lilypink (talk) 18:09, 28 January 2009 (UTC)[reply]

Two-component systems are by definition systems containing a histidine kinase and a response regulator. However, eukaryotic two-component systems almost exclusively diverge from histidine kinases. An example are the phytochromes of plants, which are HK homologues which have serine/threonine kinase activity. Silasmellor (talk) 20:51, 2 April 2010 (UTC)[reply]

Figure of His Kinase A (phospho-acceptor) domain[edit]

Figure of His Kinase A (phospho-acceptor) domain makes no sense as there are shown 21 unaligned NMR models (of the same domain). In fact, the domain is much more simple - it is a 4-helical coiled coil. — Preceding unsigned comment added by 147.173.212.105 (talk) 13:46, 14 February 2013 (UTC)[reply]