Talk:Estriol

This is the talk page for discussing improvements to the Estriol article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Molecular Biology: MCB

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

Chemicals Low‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles
Low	This article has been rated as Low-importance on the project's importance scale.

Medicine Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.

Women's Health Low‑importance

	This article is within the scope of WikiProject Women's Health, a collaborative effort to improve the coverage of Women's Health on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Women's HealthWikipedia:WikiProject Women's HealthTemplate:WikiProject Women's Healthwomen's health articles
Low	This article has been rated as Low-importance on the importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Estriol.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Untitled[edit]

The limited research I have done indicates that the estriol is primarily produced by the placenta rather than the fetus. WebMD reference [1]

References[edit]

This article needs some type of reference, added tag. --FloNight 20:39, 22 November 2005 (UTC)[reply]

FDA headsup[edit]

The MS study needs verifying, particularly since the FDA has started to crack down on estriol prescriptions, and it's become a point of contention. —Preceding unsigned comment added by 143.231.249.141 (talk) 19:42, 7 July 2008 (UTC)[reply]

"[S]everal studies have demonstrated an inverse relationship between estriol levels and breast cancer as well as antitumor effects of estriol.27,111-113 ..." PMID 17217322[edit]

Deborah Moskowitz, ND

A Comprehensive Review of the Safety and Efficacy of Bioidentical Hormones for the Management of Menopause and Related Health Risks

Bioidentical Hormones Review

PMID 17217322

Free full text http://www.altmedrev.com/publications/11/3/208.pdf

"...It is well understood that, due to proliferative effect on normal breast cells as well as on numerous breast cancer cell lines, estrogens are contraindicated for women at risk for breast cancer, because, as referenced above, increased estrone and estradiol levels are associated with an increased risk of breast cancer. The supplementation of either of these forms of estrogen increases serum estradiol and estrone due to the pathways by which they are metabolized. In contrast, several studies have demonstrated an inverse relationship between estriol levels and breast cancer as well as antitumor effects of estriol.27,111-113 ... "

...

27. Follingstad AH. Estriol, the forgotten estrogen? JAMA 1978;239:29-30.

...

111. Lemon HM, Wotiz HH, Parsons L, Mozden PJ. Reduced estriol excretion in patients with breast cancer prior to endocrine therapy. JAMA 1966;196:1128-1136.

112. Lemon HM. Pathophysiologic considerations in the treatment of menopausal patients with oestrogens; the role of oestriol in the prevention of mammary carcinoma. Acta Endocrinol Suppl (Copenh) 1980;233:17-27.

113. Lemon HM. Estriol prevention of mammary carcinoma induced by 7,12- dimethylbenzanthracene and procarbazine. Cancer Res 1975;35:1341-1353.

[emphasis added] — Preceding unsigned comment added by 99.190.133.143 (talk) 00:22, 5 February 2012 (UTC)[reply]