Talk:DNA methyltransferase

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Intro Contains Irrelevant Info[edit]

In the intro: "A simple and accurate method for quantification of cytosine methylation in any DNA region can be obtained by using bisulfite sequencing. Bisulfite treatment converts all unmethylated cytosine into uracil and leaves methylated cytosine intact. This modified DNA is then amplified by polymerase chain reaction (PCR). During PCR, uracil is read as thymidine by low fidelity DNA polymerase. Only methylated cytosine in the initial sequence remains as the sequences of C (but are no longer methylated) whereas other unmethylated C sites appear as T sequences. Following bisulfite PCR, individual DNA strands can be subcloned and sequenced. All remaining cytosines are indications of a methylated cytosine in the original DNA template." - this does not belong here. It's only losely related to the topic of methyltransferase and certainly isn't a summary of what is contained in the body of the article. I suggest moving it to the closest article to cytosine methylation. --Seans Potato Business 23:01, 8 February 2007 (UTC)[reply]

I had exactly the same thought, and was about to leave a similar comment. Now that I see you already mentioned this, and there have been no objections, I'm going to go ahead and erase this section. There is actually already an article for bisulfite sequencing, but I see no need to link it from here. It is more relevant to the DNA methylation article, which does link to it. -Madeleine 22:50, 14 March 2007 (UTC)[reply]